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Thyroid Peroxidase(TPO)
Thyroid peroxidase (TPO) is an enzyme expressed in the thyroid. TPO oxidizes the iodine ion to form an iodine atom, which binds to the thyroglobulin's tyrosine residues to produce thyroxine (T4) and triiodothyronine (T3). The expression of TPO gene is regulated by thyroid stimulating hormone. In the normal thyroid, TPO shows diffuse in all follicular cells with granular cytoplasmic staining. The expression level of TPO in thyroid cancer is lower than that of normal thyroid and benign thyroid tumors.
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Staining Tissue
- As Figure shows:
Lymphocytic thyroiditis tissue stained with TPO
Specification
|
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
|
CTR-0161 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
More Info
Clone: EP159
Source: Rabbit
Localization: Cytoplasm
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section
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