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SOX-10, anti-rabbit, EP268

SOX-10 (Sry-relaed HMG-BOX gene 10) is a nuclear transcription factor involved in the development of nerves and the differentiation of melanocyte cell lines. It has recently been shown to be a sensitive marker for melanoma (including conventional, fusiform, and connective tissue hyperplasia). SOX-10 is expressed in 97% of melanomas and 49% of malignant schwannomas. SOX-10 is often expressed to be positive in connective tissue hyperplasia and spindle cell melanoma, but negative in HMB45 and MelanA.

Staining Tissue

  • As Figure shows:

Malignant melanoma tissue stained with SOX-10

Specification

CODE

 WORKING  SOLUTION

CONCENTRATED SOLUTION

CSR-0180

SPECIFICATION

1ml

3ml

6ml

0.1ml

0.2ml

More Info

Clone:  EP268

Source: Rabbit

Localization: Nucleus

Pretreatment:  Thermal remediation

Applicable tissue: Paraffin section

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