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MicroStacker™ Ultra Polymer Detection system, utilizing the "micro-polymer stacking method," is an innovation independently developed by Celnovte biotechnology R&D team. It represents a breakthrough in four core technologies: micropolymer scaffold, HRP layering, Fab' labeling, and Conjugation chemistry, for which it has been granted a national invention patent. This innovation marks the first domestically produced micro-polymer scaffold detection system, breaking the monopoly of imported products.
The MicroStacker™ technology allows well-controlled layered stacking of F(ab’) fragments of IgG secondary antibody and peroxidase enzymes on a micro-polymer scaffold, which results in a compact polymeric structure with superior sensitivity compared to other conventional HRP polymers with bulky dextran backbones. This system avoids the use of streptavidin and biotin, and therefore eliminates non-specific staining as a result of endogenous biotin. Herein, the Mouse-on-Mouse Polymer comprises of specially engineered anti-Mouse secondary antibody to eliminate the high backgrounds caused by endogenous mouse antibodies in mouse tissues.