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p16 and Ki-67 are pivotal biomarkers for cervical precancer detection, serving as important indicators of cell cycle regulation and proliferation. The p16 protein is typically expressed in response to the activation of oncogenes such as HPV, while Ki-67 reflects cellular growth.
PASM-Masson staining is a crucial histological technique utilized in pathological diagnosis that highlights specific tissue components. This staining method applies the combination of periodic acid-Schiff (PAS) and Masson’s trichrome, aiding in the differentiation of various cellular structures.
Test results from an IHC stainer play a pivotal role in both diagnostics and subsequent treatment pathways. The accurate interpretation of these results can lead to tailored therapeutic strategies that align with a patient's specific condition.
HER2 positive cancer refers to a type of cancer that tests positive for the human epidermal growth factor receptor 2 (HER2) protein. This receptor is part of a network that regulates cell growth and division. When there is an overexpression of HER2, it leads to more aggressive tumor growth and a higher likelihood of metastasis.