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In aerobic respiration, succinate dehydrogenase catalyzes succinate and ubiquinone to be fumarate and panthenol respectively. SDH protein is composed of four subunits: yellow pigment subunit (SDHA), iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD). Mutations in these subunits can cause different mitochondrial dysfunctions.
Pheochromocytoma tissue stained with SDHB
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
CSM-0270 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
Clone: 21A11AE7
Source: Mouse
Localization: Membrane
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section