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Home Product IMMUNOHISTOCHEMISTRY PRIMARY ANTIBODY Retinoblastoma Gene Protein (Rb)

Retinoblastoma Gene Protein (Rb)

Retinoblastoma (Rb) is a rare retinoblastoma associated with a chromosomal mutation of chromosome 13. Additionally ,nucleus phosphoprotein is coed by Rb tumor suppressor gene. This Rb is exist in many cells and to regulate cell growth by activating the transcription factor ATP-2 indirectly. Then,ATP-2 activation initiates the expression of TGF-β2, TGF-B2 inhibits gene transcription to affect cell growth in turn afterward. The two-sided Rb gene mutation may potentially play a role in the development of many malignant tumors.

Staining Tissue

  • As Figure shows:

Colon cancer tissue stained with Rb(Mouse)

Specification

CODE

 WORKING  SOLUTION

CONCENTRATED SOLUTION

CRM-0010

SPECIFICATION

1ml

3ml

6ml

0.1ml

0.2ml

More Info

Clone: 1F8

Source: Mouse

Localization: Nucleus

Pretreatment:  Thermal remediation

Applicable tissue: Paraffin section/Frozen section

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