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Melanoma Marker (CD63)

HMB45 antigens are also used to identify retinal pigment epithelial (RPE), but the literature reports that it reacts only to RPE before birth and during a short period of infancy. Its reaction to intradermal nevus and normal melanin and non-melanocytes in adults was not observed. Besides, They were negative in epithelial, lymphatic, glial and mesenchymal tumor cells. The clone is detailed in the literature, indicating that it can mark the intracellular antigens of most melanomas and other tumors with melanoma as well as melanoma cell differentiation characteristics. The document also reports that the clone reacts with the junctional nevus and blue nevus cells.

Staining Tissue

  • As Figure shows:

Human metastatic melanoma tissue stained with Melanoma Marker(CD63)

Specification

CODE

 WORKING  SOLUTION

CONCENTRATED SOLUTION

CMM-0150

SPECIFICATION

1ml

3ml

6ml

0.1ml

0.2ml

More Info

Clone:  HMB45

Source: Mouse

Localization: Cytoplasm

Pretreatment: Thermal remediation

Applicable tissue: Paraffin section/Frozen section

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