IgG4(MRQ-44),MMab

IgG4 is a low proportion of IgG subtypes that account for only 3% to 6% of the total IgG of normal human serum. IgG4-related sclerosing disorders are a syndrome that has only recently been known. Its characteristics are characterized by multiple organ-like lesions, such as the pancreas, bile ducts, gallbladder, tear glands, salivary glands, post-peritoneal, kidney, lung, breast, thyroid and prostate, etc. A large number of lymphocytes and plasma cells in the lesions are soaked and metalysis hardened, and IgG4 titre of serum increased as well as IgG4 and plasma cells of tissue were increased. But patients can benefit from steroid therapy, then clinical prognosis is good. The results of immunohistochemistry studies in IgG4-related sclerosis cases showed that IgG4 had a significant increase in the lesions of the disease and a significant increase in the ratio of IgG4\/IgG in tissues.

Staining Tissue

[As Figure shows]

Tonsil tissue stained with Immunoglobulin G4(Mouse)

[Intended Use]

IgG4 is a low proportion of IgG subtypes that account for only 3% to 6% of the total IgG of normal human serum. IgG4-related sclerosing disorders are a syndrome that has only recently been known. Its characteristics are characterized by multiple organ-like lesions, such as the pancreas, bile ducts, gallbladder, tear glands, salivary glands, post-peritoneal, kidney, lung, breast, thyroid and prostate, etc. A large number of lymphocytes and plasma cells in the lesions are soaked and metalysis hardened, and IgG4 titre of serum increased as well as IgG4 and plasma cells of tissue were increased. But patients can benefit from steroid therapy, then clinical prognosis is good. The results of immunohistochemistry studies in IgG4-related sclerosis cases showed that IgG4 had a significant increase in the lesions of the disease and a significant increase in the ratio of IgG4\/IgG in tissues.

 

[Specifications]

Product Name IgG4(MRQ-44),MMab
Catalog No. CIM-0130
Intended Use IVD, RUO
Species Reactivity Human; others not tested
Cellular Localization Cytoplasm / Nucleus
Antibody Type Mouse Monoclonal
Clone MRQ-44
Format and Volume Ready-to-use: 1mL, 3mL, 6mL   Concentrated: 0.1mL, 0.2mL and 1mL 

 

[Datasheets & SDS]

IVD Datasheet (IFU) ↕️ Download 
RUO Datasheet (IFU) ↕️ Download 
SDS sheet check with sales 

 

[Storage and Validity]

Store at 2~8°C. Avoid freezing. 
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

 

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