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GranzymeB(GrB)

Granulase is an exogenous serine protease produced by cytotoxic T cells and cytoplasmic particles of natural killer cells. Their role is to induce the natural apoptosis of the infected cells, thus destroying the infected cells. Granulase antibodies are used to detect natural killer cells, T-cell lymphoma, and mesodestatic large cell lymphoma. In Hodgkin's lymphoma, the presence of high percentages of toxic T-cells is a poor prognostic indicator.

Staining Tissue

  • As Figure shows:

Neck lymphoma tissue stained with GranzymeB(GrB)

Specification

CODE

 WORKING  SOLUTION

CONCENTRATED SOLUTION

CGR-0211

SPECIFICATION

1ml

3ml

6ml

0.1ml

0.2ml

More Info

Clone: EP230

Source: Rabbit

Localization: Cytoplasm

Pretreatment: Thermal remediation

Applicable tissue: Paraffin section

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