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GATA1

GATA1, a member of the GATA family, was first discovered and expressed in the early erythrocytes,megakaryocyte,eosnophils,mastocyte, testicular substrate Sertoli cell, non-hematopoietic embryonic stem cells. The transcription factor GATA1 plays an important biological role in the proliferation and differentiation of normal red blood cells and controls the differentiation of megakaryocyte, mast cells and eosinophilic cells.The transcription factor ,GATA1, can interact with many biological macromolecules, such as erythropoietin (EPO) FOG(friend of GATA) GATA2, which plays an important biological effect in the pathogenesis of multiple myeloma and leukemia as well as thrombocytopenia.

Staining Tissue

  • As Figure shows:

Bone marrow megakaryocyte tissue stained with GATA1

Specification

CODE

 WORKING  SOLUTION

CONCENTRATED SOLUTION

CGM-0120

SPECIFICATION

1ml

3ml

6ml

0.1ml

0.2ml

More Info

Clone: 4F5

Source: Mouse

Localization: Nucleus

Pretreatment: Thermal remediation

Applicable tissue: Paraffin section

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