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Human von Willebrand factor (or factor VIII-related antigen is 270 kD multimeric plasma glycoprotein. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib/IIIa, collagen and heparin. von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular origin.
Connective tissue stained with Human von Willebrand Factor
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
CFR-0021 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
Clone: Polyclonal
Source: Rabbit
Localization: Cytoplasm
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section