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E2A Breakapart Detection Kit

Clinic Signification:
1.E2A gene can be fused with PBX1 and HLF genes, E2A/PBX1 is more common (5%), and E2A/HLF is less common (1%).
2.Approximately 5% of childhood ALL, both fusions mean poor prognosis and high risk of recurrence.
3.Karyotype analysis can easily lead to 20-25% missed diagnosis, and FISH can overcome this shortcoming.
4.These patients often relapse early after standard chemotherapy.

Contrast

E2A Normal

E2A Breakapart

More Info

Probe Description: E2A

Cat.No.: CF1253

Specification: 10 tests/box, 20 tests/box

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