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Keratins are a family of insoluble proteins with a molecular weight of 40 to 70kD. These proteins form elasticities in the epidermis and almost all other epithelium. They are intermediate filaments
As with cell development, differentiation of the normal epidermis is characterized by a series of morphological and biochemical changes, from the basal germinal layer through the spinous granular layer to the outer keratinized layer The specific expression of 56kD keratin and 65kD to 67kD keratin in the whole process of epithelial cell terminal differentiation can be considered as the molecular marker of keratinization.
Breast cancer tissue stained with Cytokeratin Pan
CODE |
WORKING SOLUTION |
|||
CCM-0960 |
SPECIFICATION |
1ml |
3ml |
6ml |
Clone: AE1/AE3
Source: Mouse
Localization: Cytoplasm
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section/Frozen section