Cytokeratin Pan (AE1/AE3), MMab

Keratins are a family of insoluble proteins with a molecular weight of 40 to 70kD. These proteins form elasticities in the epidermis and almost all other epithelium. They are intermediate filaments
As with cell development, differentiation of the normal epidermis is characterized by a series of morphological and biochemical changes, from the basal germinal layer through the spinous granular layer to the outer keratinized layer The specific expression of 56kD keratin and 65kD to 67kD keratin in the whole process of epithelial cell terminal differentiation can be considered as the molecular marker of keratinization.

Staining Tissue

[As Figure shows]

Breast cancer tissue stained with Cytokeratin Pan

[Intended Use]

Keratins are a family of insoluble proteins with a molecular weight of 40 to 70kD. These proteins form elasticities in the epidermis and almost all other epithelium. They are intermediate filaments
As with cell development, differentiation of the normal epidermis is characterized by a series of morphological and biochemical changes, from the basal germinal layer through the spinous granular layer to the outer keratinized layer The specific expression of 56kD keratin and 65kD to 67kD keratin in the whole process of epithelial cell terminal differentiation can be considered as the molecular marker of keratinization.

 

[Specifications]

Product Name Cytokeratin Pan (AE1/AE3), MMab
Catalog No. CCM-0960
Intended Use IVD, RUO
Species Reactivity Human; others not tested
Cellular Localization Cytoplasm / Nucleus
Antibody Type Mouse Monoclonal
Clone AE1/AE3
Format and Volume Ready-to-use: 1mL, 3mL, 6mL   Concentrated: 0.1mL, 0.2mL and 1mL 

 

[Datasheets & SDS]

IVD Datasheet (IFU) ↕️ Download 
RUO Datasheet (IFU) ↕️ Download 
SDS sheet check with sales 

 

[Storage and Validity]

Store at 2~8°C. Avoid freezing. 
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

 

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