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CMYC Breakapart Detection Kit

Clinic Signification：
1.Burkitt lymphoma (BL) is a highly invasive B-cell non-Hodgkin's lymphoma. About 80% of BL cases have t(8; 14) (q24; q32); about 15% of BL cases have t(2; 8) (p11; q24); about 5% have t(8; 22) (q24: q11). Chromosome translocation leading to c-myc breakapart and reorganization may be a sign of BL, which can be used in the clinical diagnosis of BL.
2.Myc gene rearrangement is one of the main causes of Myc protein expression. Myc gene amplification can also cause Myc protein expression. And recent studies have suggested that Myc gene amplification may also affect the prognosis of DLBCL patients. Therefore, the detection of different abnormal forms of the Myc gene has important clinical guidance for the correct evaluation of the patient's prognosis and the development of a reasonable treatment plan.