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Bax gene is the most important apoptotic gene in human body, which belongs to the bc1-2 gene family. The encoded Bax protein can form an heterodimer with bc1-2 to inhibit bcl-2. The ratio between Bax/ bcl-2 proteins was found to be a key factor in determining the degree of inhibition of apoptosis, so Bax was considered to be one of the most important pro-apoptotic genes.Bax is more widely expressed and can be found in liver cells, renal tubular epithelial cells, respiratory epithelial cells and bronchial smooth muscle and vascular smooth muscle cells.
Breast tissue stained with Bax
CODE |
WORKING SOLUTION |
|||
CBR-0110 |
SPECIFICATION |
1ml |
3ml |
6ml |
Clone: E63
Source: Rabbit
Localization: Cytoplasm
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section