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Alpha-1-Antitrypsin(AAT)

Alpha-1-antitrypsin is synthesized in the liver and is present in serum and tissue fluid as a protease inhibitor, especially as an elastase inhibitor.Its main function is to neutralize the release of elastase by neutrophils in the inflammatory response.The deficiency of Alpha-1-antitrypsin may lead to lung failure to inhibit tissue destruction induced by elastase. Alpha-1-antitrypsin deficiency is associated with acinar emphysema and liver disease.In the liver, deficiency of c-1-antitrypsin may cause neonatal hepatitis or cirrhosis of the liver in some individuals during adolescence or adulthood.

Staining Tissue

  • As Figure Shows:

Tonsil tissue stained with AAT

Specification

CODE

 WORKING  SOLUTION

CAR-0110

SPECIFICATION

1ml

3ml

6ml

More Info

Clone: Polyclonal

Source: Rabbit

Localization: Cytoplasm

Pretreatment: Thermal remediation

Applicable tissue: Paraffin section/Frozen section

 

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